Journal Categories
Swift Journal of Medicine and Medical Sciences (SJMMS)
August 2015 Vol. 1(2), pp. 006-011
Copyright © 2015 Swift Journals
Original Research Paper
Role of Elongation Factor EF-Tu in Bacterial Cytoskeletons - Mini Review and Update
Frank Mayer
Seerosenweg 1a DE-26160 Bad Zwischenahn, Germany
*Corresponding Author E-mail: fmayer12@gmx.de
Accepted 26 August, 2015
Abstract
The existence of bacterial cytoskeletons – besides a structural cellular element named FtsZ involved in cell division – was not known. It was even proposed that possession of a cytoskeleton is one of the major structural features of higher organisms. The situation changed when actin-related bacterial proteins and a variety of other structural elements with cytoskeletal functions were discovered. Bacterial elongation factor EF-Tu was not classified as such an element. After all, it was known as a factor involved in bacterial translation and elongation. In the meantime, however, experimental data were collected which show that EF-Tu has a double function, i.e. not only in translation and elongation, but also as an intrinsic component of bacterial cytoskeletons in general.
Keywords: Bacterial Cytoskeletons, Elongation Factor EF-Tu, EF-Tu with Double Function, Aspects of Evolution, Recombinant Bacterial Strains, Induced Bacterial Lysis, New Class of Antibacterial Agents
Read [Full Text - PDF]