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Swift Journal of Medicine and Medical Sciences (SJMMS)
October 2015 Vol. 1(3), pp. 018-022
Copyright © 2015 Swift Journals
Original Research Paper
“Exclusion Zones” in Biological Cells?
Frank Mayer
Seerosenweg 1a DE-26160 Bad Zwischenahn, Germany
*Corresponding Author E-mail: fmayer12@gmx.de
Accepted 21 September, 2015
Abstract
“Exclusion zones” (EZ) were observed as a lining of various depths on a hydrophilic surface in water-containing objects, including, most probably, hydrophilic membranes in biological cells. Indications for the presence of EZs inside living biological cells are scarce. A surprising property is that this kind of water moiety excludes any solutes, from emulsified objects down to molecules. One of the possible implications could be that, inside the cell, substrates for membrane-bound enzymes could have no access to their enzymes due to exclusion by this water moiety covering the hydrophilic membranes. A possible solution for this problem, created during evolution, is presented and discussed.
Keywords:Biological cells, structure-function relationships, hydrophilic membrane surfaces, membrane-bound enzymes, enzyme complexes with linkers, “Exclusion Zones”, solute exclusion, accessibility of substrates to enzymes
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